Ranked board
Semaglutide sellers, and whether what they say matches the trials
Semaglutide has more phase 3 evidence behind it than anything else in this category, which makes the gap between what the trials showed and what a seller says about them unusually easy to measure. Two companies here sell the same molecule and describe it completely differently. Only the semaglutide products are counted below.
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What gets on this board
Every published review whose dispensed list includes a product we have graded as semaglutide — whether that is an FDA-approved Wegovy or Ozempic pen or a 503A compounded preparation. A company that sells a GLP-1 without naming the molecule is not on the board, because there is no claim about semaglutide to grade.
What decides the order
Ranked by how much of what each company sells is described accurately — the share of the products this board counts whose marketing claim matches the trials behind it. Ties go to the company with more matching claims, then to the one that names its pharmacy, then to the one that publishes a testing regime, and last of all to alphabetical order. Nothing is pinned, sponsored, or lifted into position.
What the grading found
11/21
Claims that match the trials
Across every one of these companies' semaglutide products that we have graded.
6/16
Name their pharmacy
A telehealth brand is almost never the pharmacy that fills the order.
0
Publish a readable certificate
Of every company reviewed on this site, not just those on this board.
The ranking
Every product counted here was graded against the published trials for that molecule, using the company's own words about it. The three counts below are that grading, and they are the ranking — there is no score, no weighting and no adjustment behind them.
Only semaglutide products are counted on this board. A company's sermorelin, NAD+ or glutathione claims do not move it up or down here — those are counted on the boards that cover them.
| Company | Claims vs. trials | Discloses | Visit |
|---|---|---|---|
NovoCare Pharmacy Checked August 2026 | 3/3100%
| Pharmacy named | Visit |
Trellis Vitality Checked August 2026 | 1/1100%
| Pharmacy namedTesting shown | Visit |
Auren Rx Checked August 2026 | 1/1100%
| Pharmacy named | Visit |
1/1100%
| Testing shown | Visit | |
Regenics Checked August 2026 | 1/1100%
| Testing shown | Visit |
Valhalla Vitality Checked August 2026 | 1/1100%
| Testing shown | Visit |
AgelessRx Checked August 2026 | 1/250%
| Testing shown | Visit |
1/250%
| Testing shown | Visit | |
Vyvron Checked August 2026 | 1/250%
| Nothing published | Visit |
Invigor Medical Checked August 2026 | 0/10%
| Pharmacy namedTesting shown | Visit |
PeptidesRx Checked August 2026 | 0/10%
| Pharmacy namedTesting shown | Not linked |
The Edit Health Checked August 2026 | 0/10%
| Pharmacy namedTesting shown | Visit |
Defy Medical Checked August 2026 | 0/10%
| Nothing published | Visit |
0/10%
| Nothing published | Visit | |
Lighter You Checked August 2026 | 0/10%
| Nothing published | Visit |
Rehydra+ Wellness Checked August 2026 | 0/10%
| Nothing published | Visit |
How a claim is graded, and what moves a compound between evidence tiers, is on our methodology page.
What this board does not measure
Whether it works
A company can describe a weakly-evidenced product accurately and rank well here. What the evidence says about each molecule is on its own graded compound page, and the two questions are deliberately kept apart.
Clinical care
We read public pages. We have not been a patient of any of these companies, have not assessed a consultation, and publish no quality score of any kind.
Price
Prices appear on a review as a note where a company publishes one, and they are not part of this ranking. A cheaper company is not lower here and a dearer one is not higher.
Product quality
Not one company reviewed here publishes a certificate of analysis a customer can read. Until that changes, nothing on this site can tell you what is in a vial.
Considered, and not on this board
2 companies were inside this board's candidate net and did not meet its rule. Each one has a published review here, and none was left off for an unflattering result.
- 1st Optimal
Dispenses GLP-1 receptor agonist, molecule not named on any page that sells it — but nothing whose molecule is semaglutide, so it has no semaglutide claim of its own for us to grade.
- Hone Health
Dispenses Liraglutide — but nothing whose molecule is semaglutide, so it has no semaglutide claim of its own for us to grade.
Frequently asked questions
Is compounded semaglutide the same drug as Wegovy?
It is the same molecule and it is not the same product. Wegovy is an approved finished drug: FDA has reviewed that specific formulation, at those doses, for that indication, and it carries an NDC. A compounded preparation is made by a pharmacy against a prescription, is not FDA-approved, and is not reviewed by FDA for safety, effectiveness or quality. Both appear on this board, and each row says which one that company sells.
Why does a company selling the approved pen tend to rank higher?
Because an approved product comes with an approved label, and a label is a claim that has already been through the trials. It is much harder to overstate a drug when the sentence you are allowed to print was written from the evidence. That is a structural advantage, not a compliment, and the board shows it rather than correcting for it.
Nothing pinned
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.